Pfizer announced positive results from its late stage trials of Xtandi, its potential prostate cancer treatment along with its research partner, Astellas Pharma.

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Xtandi was incorporated into Pfizer’s stable after it acquired Medivation for US$14 billion in 2016. The trials found that when Xtandi is combined with existing prostate cancer therapy for patients whose cancer had not yet spread through the body, it improved survival rates relative to just standard prostate treatments using anti-hormones. In other words, the drug appears to have prevented metastases from developing in the trail patients.
 
There are currently no FDA-approved treatments for patients with non-metastatic castration-resistant prostate cancer and Xtandi is currently only approved for patients with metastatic disease, in which it generated US$2.3 billion in sales. Therefore, this breakthrough has the potential to expand the use of the Xtandi (along with Johnson & Johnson’s proposed rival drug, Zytiga) and increase the total addressable market size to include all patients with castration-resistant prostate cancer.

 

About Kevin Hua

Kevin Hua is a Co-Founder of AtlasTrend, an online investment platform that makes it easy for anyone to learn and invest in trends transforming our world. Kevin has over 19 years experience in financial markets including as Senior Portfolio Manager at Atrium Investment Management and Stark Investments.